Since December 2014, USDA has confirmed several cases of highly pathogenic avian influenza (HPAI) H5 in the Pacific, Central, and Mississippi flyways. The disease has been found in wild birds, as well as backyard and commercial poultry flocks. The Centers for Disease Control and Prevention (CDC) considers the risk to people from these HPAI H5 infections to be low. No human cases of these HPAI H5 viruses have been detected in the United States, Canada, or internationally. USDA and NASDA member agencies are leading the response efforts and actively working with industry on surveillance, reporting, biosecurity, movement control, vaccination and depopulation efforts to effectively mitigate and control the animal health and economic impacts of this disease.